ARTIFICIAL

ARTIFICIAL BONE GRAFTS: PRO OSTEON


Many medical situations call for a bone graft. Among them are fusions of the spine, fusions of the joints in the arms and legs, fractures, gaps in bones caused by trauma or infection, revision joint surgery and oral/maxillofacial surgery.

Americans suffer 5.6 million fractures a year, and surgeons perform nearly half a million bone graft operations annually. Bone grafts are second only to blood transfusions on the list of transplanted materials.

In a typical bone graft involving a fracture, bone or synthetic material is shaped by the surgeon to fit the affected area. It is then held in place with pins or screws that hold the healthy bone to the implanted material.

Bone grafts provide a framework into which the host bone can regenerate and heal. Bone cells weave into and through the porous microstructure of the implant. The implant provides a framework to support the new tissue, blood cells and soft tissue as they grow to connect fractured bone segments. Bone cells and living cells inside the graft may also stimulate growth of bone and other tissue.

PRO OSTEON IMPLANT 500

Safe, strong, and cost effective bone grafts are now performed using synthetic material known as Pro Osteon Implant 500. This substance facilitates the natural healing process without risking the major drawbacks of previous grafting methods, (disease transmission, biological rejection, and the additional surgery necessary to collect the bone for grafting).

Pro Osteon Implant 500, generically called "bone void filler", is a clinically proven material that has changed the way many orthopaedic surgeons do bone grafts. It is sterile, biocompatible (meaning the bodyís immune system does not reject it), and it is easily sculpted to fill a defect in fractured bones. In some 20,000 procedures using Pro Osteon, there has not been a single case of rejection. Pro Osteon is fully approved by the Food and Drug Administration for metaphyseal fracture defects, which are typically fractures at the ends of the long bones of the arms and legs, when used with rigid internal fixation (plates, pins, screws, etc.)

A SAFE SOLUTION FROM THE SEA

What makes this synthetic bone graft material effective? Pro Osteon mimics the internal structure of human bone. This synthetic material is made by subjecting a common, non-decorative form to coral to a patented chemical process which converts the coral to hydroxyapatite, the same mineral content of human bone. The porous, interconnected structure of the coral remains intact, providing an ideal matrix through which new bone tissue can grow. One coral head weighting 150 - 200 pounds provides enough material for hundreds of bone grafts.

After conversion processing, the material is no longer technically coral, but a calcium phosphate. It retains the porous, interconnected architecture of coral, which is compatible with human bone stucture. The material is osteoconductive, allowing bone cells to weave into and through it.

Figure 1: Human Cancellous Bone        Figure 2: Pro Osteon Implant 500 

In a typical surgical procedure using Pro Osteon on a long bone, the surgeon determines the amount of bone graft he needs and shapes the Pro Osteon block to fit into the damaged area. The graft area is stabilized with a metal plate, screws, or some other form of internal fixation. This protects the bone graft area so it can grow strong and durable.

Eventually, the Pro Osteon is replaced by bone, leaving the mended bone as strong as it was before it was fractured. Healing rates for Pro Osteon compare favorably to other products. Pro Osteon needs no special storage or handling. It is simply taken from the shelf and sculpted to fit the defect.

WHAT ABOUT OTHER PROCEDURES?

The use of Pro Osteon has several advantages over the two other, older bone graft techniques.

COST SAVINGS FROM PRO OSTEON

Use of Pro Osteon can substantially reduce financial costs of a bone graft - by as much a $9,000 per patient, according to a recent medical study. The study showed hospital stays could be reduced from a week for autograft procedures to just three days after a Pro Osteon graft implant. The savings, when compared to an autograft, come mainly from eliminating the need for secondary surgery, reducing operation time and reducing the length of hospital stay. Savings when compared to an allograft come by eliminating the chances of immune system rejection or reintroduction of an outside disease from cadaver bone.

Material courtesy of Interpore, 181 Technology Drive, Irvine, California, 92618-2402, 714-453-3200.


THIS MATERIAL DOES NOT CONSTITUTE MEDICAL ADVICE. IT IS INTENDED FOR INFORMATIONAL PURPOSES ONLY. PLEASE CONSULT A PHYSICIAN FOR SPECIFIC TREATMENT RECOMMENDATIONS.

THE CENTER FOR ORTHOPAEDICS AND SPORTS MEDICINE
1211 JOHNSON FERRY RD.; MARIETTA, GA., 30068
770-565-0011
http://www.arthroscopy.com




    Last Update: 04/03/2003
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